About Medium Biosciences
Medium Bio is developing new assays & AI models to design biomolecules, starting with antibodies. We believe that the most impactful AI developments will be derived from fast, accurate simulations of the biophysical world. In particular, biomolecule design will help create new therapies for various diseases, grow our understanding of nature, and create lasting abundance.
We are a venture-backed rapidly growing early stage startup. Now is the most exciting time to join us as we expand our AI & Bio team!
About the role
Skills: Biology, Cell biology, Protein engineeringAbout you
We are seeking a passionate, self-motivated scientist excited about protein design and the development of our platform. You will work with the team to design and validate assays for high-throughput multiplexed protein characterization starting with binding. You will be a part of founding team charting new path for how we design proteins.
- Experience independently designing experimental strategies, executing experiments, analyzing data
- Work successfully executing a high-throughput assay in academic or industry setting, in particular display assays
- Comfortable working in fast-pace environment
- You have a growth mindset, are curious and a fast learner
- You have good written, oral and visual communications skills in English
Ideal/Pluses:
- Experience with designing, implementing, and validating new genetic circuits for specific functional reporters
- Experience with engineering mammalian cell lines (e.g. growing, transfecting, troubleshoot, etc)
- Experience with developing and integrating biochemical models to analyze and tune experimental design
About the role:
We are looking for candidates who are excited about the opportunity to join the founding team and play an expanding role in the company. Your responsibilities will include:
- Development and execution of high throughput library construction and molecular cloning
- Design, execution, and fine-tune new in-vitro display techniques (yeast, phage)
- NGS and nanopore sequence prep, data collection, and analysis
- Protein expression and characterization (e.g. bacteria protein expression, stability, ELISA, SPR, etc)
- Work with CROs on to execute on some experiments
- Reviewing new literature and integrating findings into experimental design and implementation.
Technology
We are perform biological experiments and build AI models to generate protein structure & sequence performing given biological function. Computational tools we use include:
- Machine Learning: Pytorch, Pytorch Geometric, JAX
- MLOps: AWS, GitHub, Weights & Biases
