Research Associate III / Senior Research Associate

BridgeBio • Fulltime • San Bruno, CA, USA, United States • $105k - $115k / year • 3m ago

About BridgeBio Oncology Therapeutics

BridgeBio Oncology Therapeutics (“BBOT”) is a private biotech company dedicated to developing innovative new therapeutics to address dire unmet needs in oncology. Founded on a commitment to patients, scientific excellence, and operational agility, we understand that every minute counts in our efforts to develop new therapies to transform the lives of people living with cancer. Driven by a team of experienced scientists, clinicians, and industry experts, our team utilizes cutting-edge structure-based drug discovery techniques to target some of oncology’s most challenging and validated molecular targets, including KRAS and PI3Kα. BBOT has a pipeline of several promising differentiated drug candidates and strong investor support, the combination of which positions us to deliver meaningful benefit to patients. Our offices and laboratory are in South San Francisco, though our colleagues and collaborators span the country and globe.

To learn more, visit us at bridgebiooncology.com

Who You Are

This is an exciting opportunity for a highly motivated Research Associate III / Senior Research Associate to contribute to drug discovery activities for the development of novel small molecule cancer therapeutics as part of our cancer biology discovery team.
The successful candidate will collaborate with team members to conduct a variety of in vivo and ex vivo oncology research techniques including: biochemistry, molecular, cellular biology, and rodent oncology models.
This position also requires some lab management and operational tasks. We are looking for a talented and enthusiastic individual, who thrives in a collaborative, fast-paced and growing environment to join our team.
Responsibilities
Execution of in vivo (tumor cell inoculations, dosing (po, sc, ip, iv), and blood sampling) and ex vivo pharmacology experiments (target and mechanism engagement) to assess the inhibition or activation of novel targets in the oncology setting
Assist in the planning and design of model development, PK/PD, tolerability, and efficacy studies using mostly (but not limited to) small molecule therapeutics
Graph, interpret, and communicate experimental data
Maintain records in written and electronic laboratory notebooks
Manage lab inventory and equipment
Understand and implement applicable regulations around animal care/safety/handling

Education, Experience & Skills Requirements

Highly motivated, committed individual with good organizational skills
BS/MS in a biology-related discipline
BS and >3 years, or MS and >2 year hands-on experience in a cell/molecular biology laboratory (oncology setting highly preferred.
Experience with oncology in vivo models: xenografts and syngeneic, tumor measurements, ex-vivo pharmacodynamics
Experience with mammalian cell culture, test article formulation, protein expression quantification (ELISA, MSD), qPCR, and western blot/immunoprecipitation
Experience with analyzing and presenting study results
Industry experience preferred
Strong written and oral communication skills

What We Offer

A culture inspired by our values: put patients first, think independently, be radically transparent, every minute counts, and let the science speak.
A place where you own the vision – both for your program and your own career path
A collaborative, fast-paced, data-driven environment where we inspire ourselves and each other to always perform at the top of our game.
Robust and market-competitive compensation & benefits package (Base, Performance Bonus, Equity, health, welfare & retirement programs)
Flexible PTO
Rapid career advancement for strong performers
Commitment to Diversity, Equity & Inclusion

At BridgeBio, we strive to provide a market-competitive total rewards package, including base pay, an annual performance bonus, company equity, and generous health benefits. Below is the anticipated salary range for candidates for this role who will work in California. The final salary offered to a successful candidate will depend on several factors that may include but are not limited to the type and length of experience within the job, type, and length of experience within the industry, educational background, location of residence and performance during the interview process. BridgeBio is a multi-state employer, and this salary range may not reflect positions based in other states.

Salary

$105,000—$115,000 USD